Resource

Id: gene_properties/gene_sets/main
Type: gene_set_collection
Version: 0
Summary:
Description:
Labels:

Gene set ID: main

Statistics:

Number of gene sets: 15

Number of unique genes: 10578

Count of genes per gene set
main
Count of gene sets per gene
main
Gene Set Gene Count Description
non-essential genes 3811 Georgi B., et al. From mouse to human: evolutionary genomics analysis of human orthologs of essential genes. PLos Genetics (2013)
essential genes 2472 Georgi B., et al. From mouse to human: evolutionary genomics analysis of human orthologs of essential genes. PLos Genetics (2013)
CHD8 target genes 2158 Cotney J, et al. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Nat Commun. (2015)
brain embryonically expressed 1912 Iossifov I., et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014)
brain critical genes 1744 Uddin M, et al. Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder. Nat Genetics (2014)
PSD 1445 Bayes A., et al. Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nature Neuroscience (2011)
FMRP Tuschl 939 Ascano M., et al. FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012)
FMRP Darnell 842 Darnell JC., et al. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011)
chromatin modifiers 428 Iossifov I., et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014)
autism candidates from Iossifov PNAS 2015 239 Iossifov I., et al. Low load for disruptive mutations in autism genes and their biased transmission. PNAS (2015)
synaptic clefts excitatory 194 Ken H. Loh, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell (2016)
postsynaptic inhibition 181 Akiyoshi Uezu, et al. Identification of an elaborate complex mediating postsynaptic inhibition. Science (2016)
topotecan downreg genes 154 King IF, et al. Topoisomerases facilitate transcription of long genes linked to autism. Nature (2013)
autism candidates from Sanders Neuron 2015 65 Sanders S., et. al, Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci. Neuron (2015)
synaptic clefts inhibitory 41 Ken H. Loh, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell (2016)

Gene sets directory:

GeneSets

Format: directory

Web label: Main

Web label: key| (|count|): |desc

Files

Filename Size md5
GeneSets/CHD8_target_genes.txt 14.19 KB eec5158186654febb7f60561a3df0480
GeneSets/FMRP_Darnell.txt 5.31 KB 14390c88d035ebc2f4c0d4043d6d73f2
GeneSets/FMRP_Tuschl.txt 5.84 KB a86e9a552e5e7aa70eca42e986c6033b
GeneSets/PSD.txt 8.85 KB 1078be40e769e7073979a9914f7fc64f
GeneSets/autism_candidates_from_Iossifov_PNAS_2015.txt 1.61 KB 1281a753df8f03d6e554fbde6f23c197
GeneSets/autism_candidates_from_Sanders_Neuron_2015.txt 570.0 B e699d53b6c5e0d53e3cf66a9e2200542
GeneSets/brain_critical_genes.txt 11.21 KB d16fdb38521b2faa86e7805a07aa7d41
GeneSets/brain_embryonically_expressed.txt 12.0 KB 81123bad90bc5030585773a29493b49d
GeneSets/chromatin_modifiers.txt 2.7 KB c8e8bedc41cfb53939fcddca65fda04e
GeneSets/essential_genes.txt 14.37 KB 1b851d091e976f8866122ac64e9c0181
GeneSets/non_essential_genes.txt 22.56 KB 178ca1828b0777ce64f3050c4014b1be
GeneSets/postsynaptic_inhibition.txt 1.7 KB e2408fefa11807012dbe132ff9df6325
GeneSets/synaptic_clefts_excitatory.txt 1.37 KB 2179d4eca0b9288f7084c710caa143ad
GeneSets/synaptic_clefts_inhibitory.txt 402.0 B 46b2e914e9e78b6025c84573b3f42322
GeneSets/topotecan_downreg_genes.txt 1.1 KB 0d92c98049c6d5452dd77dd89b23f36e
genomic_resource.yaml 401.0 B 14b275660cccf78074c789a8b1968887
statistics/