| Id: | hg19/scores/CADD | 
| Type: | allele_score | 
| Version: | 0 | 
| Summary: | 
                     CADD score for functional prediction of a SNP  | 
            
| Description: | 
                    CADDPlease refer to Kircher et al. (2014) Nature Genetics 46(3):310-5 for details. The larger the score the more likely the SNP has damaging effect. Downloaded from https://cadd.gs.washington.edu/download ; Higher values of raw scores have relative meaning that a variant is more likely to be simulated (or "not observed") and therefore more likely to have deleterious effects. Scaled scores are PHRED-like (-10*log10(rank/total)) scaled C-score ranking a variant relative to all possible substitutions of the human genome (8.6x10^9). Please note the following copyright statement for CADD: "CADD scores (http://cadd.gs.washington.edu/) are Copyright 2013 University of Washington and Hudson-Alpha Institute for Biotechnology (all rights reserved) but are freely available for all academic, non-commercial applications. For commercial licensing information contact Jennifer McCullar (mccullaj@uw.edu).  | 
            
| Labels: | 
                
                    
  | 
            
| ID | Type | Default annotation | Description | Histogram | Range | 
|---|---|---|---|---|---|
| cadd_raw | float | 
                     cadd_raw  | 
            
            
                 CADD raw score for functional prediction of a SNP. The larger the score 
the more likely the SNP has damaging effect
 
                
                    
                        Small values desc: less damaging
                     
                
                
                    
                        Large values desc: more damaging
                     
                
             | 
            
                
                
                ![]()  | 
            [-7.54, 35.8] | 
| cadd_phred | float | 
                     cadd_phred  | 
            
            
                 CADD phred-like score. This is phred-like rank score based on whole
genome CADD raw scores. The larger the score the more likely the SNP
has damaging effect.
 
                
                    
                        Small values desc: less damaging
                     
                
                
                    
                        Large values desc: more damaging
                     
                
             | 
            
                
                
                ![]()  | 
            [0, 99] | 
| Filename | Size | md5 | 
|---|---|---|
| CADD.bedgraph.gz | 79.37 GB | 3a766a8e17649754371fdcafd4d1438d | 
| CADD.bedgraph.gz.dvc | 91.0 B | 61b8c446d51719165655dd42b1ee5536 | 
| CADD.bedgraph.gz.tbi | 2.6 MB | 757558e9cc3731ea7ce629ff35ebb7b7 | 
| CADD.bedgraph.gz.tbi.dvc | 91.0 B | 89e4400ddd3349702b7654ff5ab5935c | 
| genomic_resource.yaml | 2.38 KB | 09e5c171f68fccfa0d7f833cbefd7ce9 | 
| statistics/ |