Resource

Id: gene_properties/gene_sets/relevant
Type: gene_set_collection
Version: 0
Summary:
Description:
Labels:

Gene set ID: relevant

Statistics:

Number of gene sets: 13

Number of unique genes: 10551

Count of genes per gene set
relevant
Count of gene sets per gene
relevant
Gene Set Gene Count Description
non-essential genes 3811 Georgi B., et al. From mouse to human: evolutionary genomics analysis of human orthologs of essential genes. PLos Genetics (2013)
essential genes 2472 Georgi B., et al. From mouse to human: evolutionary genomics analysis of human orthologs of essential genes. PLos Genetics (2013)
CHD8 target genes 2158 Cotney J, et al. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Nat Commun. (2015)
brain embryonically expressed 1912 Iossifov I., et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014)
brain critical genes 1744 Uddin M, et al. Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder. Nat Genetics (2014)
PSD 1445 Bayes A., et al. Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nature Neuroscience (2011)
FMRP Tuschl 939 Ascano M., et al. FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature (2012)
FMRP Darnell 842 Darnell JC., et al. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell (2011)
chromatin modifiers 428 Iossifov I., et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature (2014)
synaptic clefts excitatory 194 Ken H. Loh, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell (2016)
postsynaptic inhibition 181 Akiyoshi Uezu, et al. Identification of an elaborate complex mediating postsynaptic inhibition. Science (2016)
topotecan downreg genes 154 King IF, et al. Topoisomerases facilitate transcription of long genes linked to autism. Nature (2013)
synaptic clefts inhibitory 41 Ken H. Loh, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell (2016)

Gene sets directory:

RelevantGeneSets

Format: directory

Web label: Relevant Gene Sets

Web label: key| (|count|): |desc

Files

Filename Size md5
RelevantGeneSets/CHD8_target_genes.txt 14.19 KB eec5158186654febb7f60561a3df0480
RelevantGeneSets/FMRP_Darnell.txt 5.31 KB 14390c88d035ebc2f4c0d4043d6d73f2
RelevantGeneSets/FMRP_Tuschl.txt 5.84 KB a86e9a552e5e7aa70eca42e986c6033b
RelevantGeneSets/PSD.txt 8.85 KB 1078be40e769e7073979a9914f7fc64f
RelevantGeneSets/brain_critical_genes.txt 11.21 KB d16fdb38521b2faa86e7805a07aa7d41
RelevantGeneSets/brain_embryonically_expressed.txt 12.0 KB 81123bad90bc5030585773a29493b49d
RelevantGeneSets/chromatin_modifiers.txt 2.7 KB c8e8bedc41cfb53939fcddca65fda04e
RelevantGeneSets/essential_genes.txt 14.37 KB 1b851d091e976f8866122ac64e9c0181
RelevantGeneSets/non_essential_genes.txt 22.56 KB 178ca1828b0777ce64f3050c4014b1be
RelevantGeneSets/postsynaptic_inhibition.txt 1.7 KB e2408fefa11807012dbe132ff9df6325
RelevantGeneSets/synaptic_clefts_excitatory.txt 1.37 KB 2179d4eca0b9288f7084c710caa143ad
RelevantGeneSets/synaptic_clefts_inhibitory.txt 402.0 B 46b2e914e9e78b6025c84573b3f42322
RelevantGeneSets/topotecan_downreg_genes.txt 1.1 KB 0d92c98049c6d5452dd77dd89b23f36e
genomic_resource.yaml 428.0 B 171faa27a9da9103c03bf88363a1ab34
statistics/