Scores

Likelihood that a gene is vulnerable to damaging mutation

Small values desc: less likely to be vulnerable

Large values desc: more likely to be vulnerable

Gene rank after sorting by LGD vulnerability score

Small values desc: more likely to be vulnerable

Large values desc: less likely to be vulnerable

Intolerance of a gene to genetic variants

Small values desc: more intolerant

Large values desc: less intolerant

Gene rank after sorting by RVIS intolerance score

Small values desc: more intolerant

Large values desc: less intolerant

LGD and RVIS average rank

Small values desc: more intolerant

Large values desc: less intolerant